Cross-Framework Mapping

21 CFR Part 211 — Current Good Manufacturing PracticevsCISA Cross-Sector Cybersecurity Performance Goals (CPG) 2.0

See exactly how 21 CFR Part 211 — Current Good Manufacturing Practice controls map to CISA Cross-Sector Cybersecurity Performance Goals (CPG) 2.0. Pre-computed mappings, identified gaps, and coverage analysis.

3
Controls Mapped
54
Gaps Found
4%
Coverage

According to the TheArtOfService Compliance Knowledge Graph:

21 CFR Part 211 — Current Good Manufacturing Practice maps to CISA Cross-Sector Cybersecurity Performance Goals (CPG) 2.0 with 4% coverage across 2 directly mapped controls. Analysis of 57 21 CFR Part 211 — Current Good Manufacturing Practice controls identifies 55 compliance gaps — primarily concentrated in Subpart F — Production and Process Controls.

Source: TheArtOfService Knowledge Graph | 57 controls analysed | 693 frameworks | 819K+ cross-framework mappings

Control Mappings

Showing 3 of 3 mapped controls across 2 domains. Sign up to explore all 819K+ mappings across 693 frameworks.

Subpart A — General Provisions(1 mappings)

CFR211-A-3Section 211.3 — Definitions
CPG-6.BSupply Chain Incident Reporting

Subpart J — Records and Reports(2 mappings)

CFR211-J-184Section 211.184 — Component, Drug Product Container, Closure, and Labeling Records2 targets
CPG-6.AVendor/Supplier Cybersecurity Requirements
CPG-6.BSupply Chain Incident Reporting

Related Comparisons

Other 21 CFR Part 211 — Current Good Manufacturing Practice comparisons

Other CISA Cross-Sector Cybersecurity Performance Goals (CPG) 2.0 comparisons

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What are the key differences between 21 CFR Part 211 — Current Good Manufacturing Practice and CISA Cross-Sector Cybersecurity Performance Goals (CPG) 2.0?

21 CFR Part 211 — Current Good Manufacturing Practice has 57 controls across its framework, while CISA Cross-Sector Cybersecurity Performance Goals (CPG) 2.0 covers 40 controls. Direct mapping analysis identifies 2 overlapping controls (4% coverage). The frameworks diverge most significantly in Subpart F — Production and Process Controls, where 8 21 CFR Part 211 — Current Good Manufacturing Practice controls have no direct CISA Cross-Sector Cybersecurity Performance Goals (CPG) 2.0 equivalent.

How many controls map between 21 CFR Part 211 — Current Good Manufacturing Practice and CISA Cross-Sector Cybersecurity Performance Goals (CPG) 2.0?

Of 57 total 21 CFR Part 211 — Current Good Manufacturing Practice controls, 2 map directly to CISA Cross-Sector Cybersecurity Performance Goals (CPG) 2.0 controls — representing 4% coverage. The remaining 55 controls represent compliance gaps requiring additional documentation or compensating controls to satisfy both frameworks simultaneously.

What are the compliance gaps when mapping 21 CFR Part 211 — Current Good Manufacturing Practice to CISA Cross-Sector Cybersecurity Performance Goals (CPG) 2.0?

55 21 CFR Part 211 — Current Good Manufacturing Practice controls have no direct equivalent in CISA Cross-Sector Cybersecurity Performance Goals (CPG) 2.0. The highest concentration of gaps is in Subpart F — Production and Process Controls with 8 unmapped controls. These gaps represent areas where additional controls, policies, or documentation must be created to achieve compliance with both frameworks.

Which control domains have the most gaps between 21 CFR Part 211 — Current Good Manufacturing Practice and CISA Cross-Sector Cybersecurity Performance Goals (CPG) 2.0?

The domain with the highest gap count is Subpart F — Production and Process Controls (8 gaps). Export the full domain-by-domain gap breakdown via the Professional tier to generate a prioritised remediation roadmap.

This platform provides educational compliance tools, not legal, regulatory, or professional compliance advice. Cross-framework mappings are AI-assisted interpretations and do not reproduce or replace official standards. Framework names and trademarks belong to their respective owners. Consult qualified professionals for your specific compliance requirements. See our Terms of Service.