NIST SP 800-66
Implementing the HIPAA Security Rule: A Guide to Protecting Electronic Protected Health Information (ePHI)
NIST SP 800-66 is a compliance framework from United States with 8 domains and 8 controls that map to 110 other frameworks. The largest domains are Business Associate Agreements (1 controls), Incident + Contingency + Evaluation (1 controls), Integration with NIST RMF, CSF, OCR Enforcement (1 controls). Every control below carries what it requires and what an assessor expects to see.
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Framework Domains (8)
Business Associate Agreements
| Code | Title |
|---|---|
| NISTSP66-4 | Business Associate Agreements (BAAs) and Third-Party ePHI Governance |
Incident + Contingency + Evaluation
| Code | Title |
|---|---|
| NISTSP66-3 | Security Incident Procedures, Contingency Plan, and Evaluation |
Integration with NIST RMF, CSF, OCR Enforcement
| Code | Title |
|---|---|
| NISTSP66-8 | Integration with NIST RMF, Cybersecurity Framework, and OCR Enforcement Posture |
Physical Safeguards
| Code | Title |
|---|---|
| NISTSP66-5 | Physical Safeguards: Facility Access, Workstation Use and Security, Device and Media Controls |
Policies, Procedures, Documentation
| Code | Title |
|---|---|
| NISTSP66-7 | Policies, Procedures, Documentation, and Organisational Requirements |
Security Management Process - Risk Analysis and Risk Management
| Code | Title |
|---|---|
| NISTSP66-1 | Security Management Process: Risk Analysis and Risk Management for ePHI |
Technical Safeguards
| Code | Title |
|---|---|
| NISTSP66-6 | Technical Safeguards: Access Control, Audit Controls, Integrity, Person Authentication |
Workforce Security + Access + Training
| Code | Title |
|---|---|
| NISTSP66-2 | Workforce Security, Information Access Management, and Awareness Training |
Your Compliance Coverage
If you comply with NIST SP 800-66, you already cover:
Turkey KVKK
50%
4 controls mapped
Compare →Privacy Act 1988 (Australia)
50%
4 controls mapped
Compare →ISO 27799:2025
50%
4 controls mapped
Compare →+ 107 more: South Korea ISMS-P (50%), AWWA Cybersecurity Guidance for the Water Sector (American Water Works Association) (50%)
See all 110 mapped frameworks ↓Maps to 110 other frameworks
Coverage is not the same as your position
This page shows what NIST SP 800-66 overlaps with in general. Where your organisation actually stands, against the standard you are going for and the certifications you already hold, is a different question. Same graph and the same recorded refutations, scoped to you rather than to a pair.
The Compliance Position Diagnostic, $5,000 fixed, ten business daysWhat is NIST SP 800-66 and who does it apply to?
NIST SP 800-66 is a compliance framework from United States with 8 domains and 8 controls. Implementing the HIPAA Security Rule: A Guide to Protecting Electronic Protected Health Information (ePHI) It is used by organisations to establish and maintain compliance with industry standards and regulatory requirements.
What does NIST SP 800-66 actually require?
NIST SP 800-66 has 8 controls organised across 8 domains. The largest domains are Business Associate Agreements (1 controls), Incident + Contingency + Evaluation (1 controls), Integration with NIST RMF, CSF, OCR Enforcement (1 controls). Each control defines specific requirements that organisations must implement to achieve compliance.
If I already comply with another framework, how much of NIST SP 800-66 do I already cover?
NIST SP 800-66 maps to 110 other compliance frameworks. The top mapping partners are Turkey KVKK (50% coverage), Privacy Act 1988 (Australia) (50% coverage), ISO 27799:2025 (50% coverage). Use our comparison tool to explore control-level mappings between frameworks.
How do I implement NIST SP 800-66?
Start your NIST SP 800-66 compliance journey by running a self-assessment on our platform to identify your current compliance posture. Our AI advisory can answer specific questions about NIST SP 800-66 requirements, and cross-framework mapping helps you leverage existing controls from other frameworks you may already comply with. Create a free account to access all 8 controls and track your progress.
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