Back to Frameworks

NIST SP 800-66

United States
vRev 2
8 domains
8 controls

Implementing the HIPAA Security Rule: A Guide to Protecting Electronic Protected Health Information (ePHI)

Verified

Framework summaries on this platform are AI-assisted interpretations for educational and compliance planning purposes. They do not reproduce or replace the official standards. Refer to the authoritative source for the definitive text. Framework names and trademarks belong to their respective organisations.

Framework Domains (8)

Business Associate Agreements

1 controls
Controls in the Business Associate Agreements domain of NIST SP 800-661 controls
CodeTitle
NISTSP66-4Business Associate Agreements (BAAs) and Third-Party ePHI Governance

Incident + Contingency + Evaluation

1 controls
Controls in the Incident + Contingency + Evaluation domain of NIST SP 800-661 controls
CodeTitle
NISTSP66-3Security Incident Procedures, Contingency Plan, and Evaluation

Integration with NIST RMF, CSF, OCR Enforcement

1 controls
Controls in the Integration with NIST RMF, CSF, OCR Enforcement domain of NIST SP 800-661 controls
CodeTitle
NISTSP66-8Integration with NIST RMF, Cybersecurity Framework, and OCR Enforcement Posture

Physical Safeguards

1 controls
Controls in the Physical Safeguards domain of NIST SP 800-661 controls
CodeTitle
NISTSP66-5Physical Safeguards: Facility Access, Workstation Use and Security, Device and Media Controls

Policies, Procedures, Documentation

1 controls
Controls in the Policies, Procedures, Documentation domain of NIST SP 800-661 controls
CodeTitle
NISTSP66-7Policies, Procedures, Documentation, and Organisational Requirements

Security Management Process - Risk Analysis and Risk Management

1 controls
Controls in the Security Management Process - Risk Analysis and Risk Management domain of NIST SP 800-661 controls
CodeTitle
NISTSP66-1Security Management Process: Risk Analysis and Risk Management for ePHI

Technical Safeguards

1 controls
Controls in the Technical Safeguards domain of NIST SP 800-661 controls
CodeTitle
NISTSP66-6Technical Safeguards: Access Control, Audit Controls, Integrity, Person Authentication

Workforce Security + Access + Training

1 controls
Controls in the Workforce Security + Access + Training domain of NIST SP 800-661 controls
CodeTitle
NISTSP66-2Workforce Security, Information Access Management, and Awareness Training

Maps to 123 other frameworks

8 total controls
Turkey KVKK
4 source controls mapped|2 target controls covered
50%
Privacy Act 1988 (Australia)
4 source controls mapped|3 target controls covered
50%
NIST SP 800-171A Rev 3 - Assessing CUI Security Requirements
4 source controls mapped|10 target controls covered
50%
ISO 13485
4 source controls mapped|13 target controls covered
50%
ISO 27799
4 source controls mapped|12 target controls covered
50%
BSI IT-Grundschutz
4 source controls mapped|11 target controls covered
50%
Annex 11 to EU GMP - Computerised Systems
4 source controls mapped|3 target controls covered
50%
ISO 27019
4 source controls mapped|4 target controls covered
50%
IEC 62443
4 source controls mapped|4 target controls covered
50%
API 1164
4 source controls mapped|4 target controls covered
50%
NIST SP 1800-32
4 source controls mapped|4 target controls covered
50%
Bahrain PDPL
4 source controls mapped|4 target controls covered
50%
APPI
4 source controls mapped|4 target controls covered
50%
ICAO Annex 17 - Aviation Security (AVSEC)
4 source controls mapped|2 target controls covered
50%
South Korea PIPA
4 source controls mapped|2 target controls covered
50%
New Jersey Data Privacy Act
4 source controls mapped|3 target controls covered
50%
50%
ISO/IEC 27011:2024
3 source controls mapped|7 target controls covered
38%
US EPA Safe Drinking Water Act (SDWA) - Cybersecurity Requirements
3 source controls mapped|1 target controls covered
38%
Protective Security Policy Framework (PSPF) Release 2024
3 source controls mapped|2 target controls covered
38%
OWASP Top 10:2025
3 source controls mapped|6 target controls covered
38%
OWASP MASVS
3 source controls mapped|4 target controls covered
38%
OWASP DevSecOps Maturity Model (DSOMM)
3 source controls mapped|3 target controls covered
38%
OWASP ASVS
3 source controls mapped|5 target controls covered
38%
OWASP API Security Top 10 - 2023
3 source controls mapped|4 target controls covered
38%
ISO/SAE 21434
3 source controls mapped|9 target controls covered
38%
ISO 27043
3 source controls mapped|9 target controls covered
38%
CISA Cross-Sector Cybersecurity Performance Goals (CPG) 2.0
3 source controls mapped|8 target controls covered
38%
MARS-E - Minimum Acceptable Risk Standards for Exchanges
3 source controls mapped|2 target controls covered
38%
ITU-T X.805 - Security Architecture for End-to-End Communications
3 source controls mapped|2 target controls covered
38%
FFIEC Cybersecurity Assessment Tool (CAT)
3 source controls mapped|5 target controls covered
38%
IEC 62351 - Power Systems Communication Security
3 source controls mapped|3 target controls covered
38%
DAMA-DMBOK2 - Data Management Body of Knowledge (2nd Edition)
3 source controls mapped|2 target controls covered
38%
ISO/IEC 27010:2015
3 source controls mapped|4 target controls covered
38%
ISO 20000-1
3 source controls mapped|2 target controls covered
38%
ISO 28001:2007 Supply Chain Security Management
3 source controls mapped|3 target controls covered
38%
ITIL 4
3 source controls mapped|1 target controls covered
38%
Canada ITSG-33 - IT Security Risk Management
3 source controls mapped|1 target controls covered
38%
IATA Operational Safety Audit (IOSA) Standards Manual
3 source controls mapped|1 target controls covered
38%
NIST Privacy Framework
3 source controls mapped|5 target controls covered
38%
FBI CJIS Security Policy
3 source controls mapped|5 target controls covered
38%
New Zealand Information Security Manual (NZISM)
3 source controls mapped|2 target controls covered
38%
FTC GLBA Safeguards Rule (16 CFR Part 314)
3 source controls mapped|2 target controls covered
38%
Vietnam Law on Cybersecurity (No. 24/2018/QH14)
2 source controls mapped|1 target controls covered
25%
Vermont Artificial Intelligence and Consumer Data Act (AICDA)
2 source controls mapped|2 target controls covered
25%
ASD Strategies to Mitigate Cyber Security Incidents
2 source controls mapped|6 target controls covered
25%
NIST SP 800-190
2 source controls mapped|7 target controls covered
25%
NIST Cybersecurity Framework 2.0
2 source controls mapped|5 target controls covered
25%
Azure Security Benchmark
2 source controls mapped|7 target controls covered
25%
AWS Well-Architected Security Pillar
2 source controls mapped|7 target controls covered
25%
AML/CTF Act 2006 (Australia)
2 source controls mapped|2 target controls covered
25%
ISO 27018
2 source controls mapped|8 target controls covered
25%
ISO 27017
2 source controls mapped|7 target controls covered
25%
Barbados Data Protection Act 2019
2 source controls mapped|3 target controls covered
25%
GDPR
2 source controls mapped|3 target controls covered
25%
ISO/IEC 27557:2022 - Organisational Privacy Risk Management
2 source controls mapped|3 target controls covered
25%
NIST AI Risk Management Framework (AI RMF 1.0)
2 source controls mapped|5 target controls covered
25%
AS9100D:2016 - Quality Management Systems for Aviation, Space, and Defence
2 source controls mapped|2 target controls covered
25%
ISO 27005
2 source controls mapped|4 target controls covered
25%
ISO/IEC 23894:2023
2 source controls mapped|4 target controls covered
25%
Nigeria Open Banking Regulatory Framework (CBN, 2023)
2 source controls mapped|2 target controls covered
25%
UK Defence Standard 05-138 - Cyber Security for Defence Suppliers
2 source controls mapped|1 target controls covered
25%
USMCA Chapter 19 - Digital Trade (United States-Mexico-Canada Agreement)
1 source controls mapped|1 target controls covered
13%
Tennessee Information Protection Act (TIPA)
1 source controls mapped|1 target controls covered
13%
TEFCA - Trusted Exchange Framework and Common Agreement
1 source controls mapped|1 target controls covered
13%
SWIFT CSCF
1 source controls mapped|1 target controls covered
13%
Regulation on the European Health Data Space (EHDS)
1 source controls mapped|1 target controls covered
13%
Russia Federal Law on Personal Data (152-FZ)
1 source controls mapped|2 target controls covered
13%
Pakistan Personal Data Protection Bill 2023
1 source controls mapped|2 target controls covered
13%
OWASP Top 10 for LLM Applications 2025
1 source controls mapped|4 target controls covered
13%
ISO/IEC 29115:2023 - Entity Authentication Assurance Framework
1 source controls mapped|4 target controls covered
13%
ISO/IEC 23837 - Security Requirements for Quantum Key Distribution
1 source controls mapped|4 target controls covered
13%
ISO 19011
1 source controls mapped|4 target controls covered
13%
13%
Armenia Law on Protection of Personal Data (2015)
1 source controls mapped|1 target controls covered
13%
Bank Secrecy Act / Anti-Money Laundering (BSA/AML)
1 source controls mapped|1 target controls covered
13%
Illinois Biometric Information Privacy Act (BIPA)
1 source controls mapped|2 target controls covered
13%
Florida Digital Bill of Rights (FDBR)
1 source controls mapped|3 target controls covered
13%
NIST SP 800-171
1 source controls mapped|1 target controls covered
13%
ISO/IEC 25012:2008 - Data Quality Model
1 source controls mapped|1 target controls covered
13%
ISO/IEC 27400:2022
1 source controls mapped|4 target controls covered
13%
ISO 22739:2024 - Blockchain and Distributed Ledger Technologies Vocabulary
1 source controls mapped|4 target controls covered
13%
ISO/IEC 27006:2024
1 source controls mapped|1 target controls covered
13%
ISO 31000:2018
1 source controls mapped|2 target controls covered
13%
13%
APRA CPS 234
1 source controls mapped|1 target controls covered
13%
Nebraska Data Privacy Act
1 source controls mapped|2 target controls covered
13%
Azerbaijan Law on Personal Data (2010)
1 source controls mapped|2 target controls covered
13%
FFIEC IT Examination Handbook
1 source controls mapped|1 target controls covered
13%
ISO 26000:2010
1 source controls mapped|1 target controls covered
13%
Austria Data Protection Act (Datenschutzgesetz, DSG, amended 2018)
1 source controls mapped|3 target controls covered
13%
FIDO2 / WebAuthn
1 source controls mapped|1 target controls covered
13%
Authorised Economic Operator (AEO) Programmes - Global Standards
1 source controls mapped|1 target controls covered
13%
Space ISAC (Information Sharing and Analysis Center) - Threat Framework
1 source controls mapped|1 target controls covered
13%
Aged Care Quality Standards (Australia)
1 source controls mapped|1 target controls covered
13%
ASIS SPC.1-2009 - Organizational Resilience Standard
1 source controls mapped|1 target controls covered
13%
US Gramm-Leach-Bliley Act (GLBA) - Higher Education Safeguards Rule
1 source controls mapped|2 target controls covered
13%
PCAOB AS 2201 - Audit of Internal Control Over Financial Reporting (ICFR)
1 source controls mapped|2 target controls covered
13%
ISO/IEC 29134:2023
1 source controls mapped|3 target controls covered
13%
ISO/IEC 27014:2020
1 source controls mapped|2 target controls covered
13%
APRA CPS 230 Operational Risk Management
1 source controls mapped|1 target controls covered
13%
ISO 31000
1 source controls mapped|3 target controls covered
13%
ISO 41001:2018 - Facility Management Systems
1 source controls mapped|1 target controls covered
13%
ISO 39001:2012 - Road Traffic Safety Management
1 source controls mapped|1 target controls covered
13%
ISO 22313:2020 - Guidance on Business Continuity Management Systems
1 source controls mapped|1 target controls covered
13%
ISO 22000
1 source controls mapped|1 target controls covered
13%
ISO/IEC 27031:2011
1 source controls mapped|1 target controls covered
13%
NFPA 1600 - Standard on Continuity, Emergency, and Crisis Management
1 source controls mapped|1 target controls covered
13%
AS9100D - Aerospace Quality Management System
1 source controls mapped|2 target controls covered
13%
ISO/IEC 27003:2017
1 source controls mapped|2 target controls covered
13%
EASA Part-IS - Information Security in Aviation
1 source controls mapped|2 target controls covered
13%
ISO/IEC 29147:2018
1 source controls mapped|1 target controls covered
13%
ISO 26262:2018 - Functional Safety for Road Vehicles
1 source controls mapped|1 target controls covered
13%
French Sapin II Law (Law No. 2016-1691)
1 source controls mapped|2 target controls covered
13%
ISO 45001
1 source controls mapped|1 target controls covered
13%

Frequently Asked Questions

What is NIST SP 800-66?

NIST SP 800-66 is a compliance framework from United States with 8 domains and 8 controls. Implementing the HIPAA Security Rule: A Guide to Protecting Electronic Protected Health Information (ePHI) It is used by organisations to establish and maintain compliance with industry standards and regulatory requirements.

How many controls does NIST SP 800-66 have?

NIST SP 800-66 has 8 controls organised across 8 domains. The largest domains are Business Associate Agreements (1 controls), Incident + Contingency + Evaluation (1 controls), Integration with NIST RMF, CSF, OCR Enforcement (1 controls). Each control defines specific requirements that organisations must implement to achieve compliance.

What frameworks does NIST SP 800-66 map to?

NIST SP 800-66 maps to 123 other compliance frameworks. The top mapping partners are Turkey KVKK (50% coverage), Privacy Act 1988 (Australia) (50% coverage), NIST SP 800-171A Rev 3 - Assessing CUI Security Requirements (50% coverage). Use our comparison tool to explore control-level mappings between frameworks.

How do I get started with NIST SP 800-66 compliance?

Start your NIST SP 800-66 compliance journey by running a self-assessment on our platform to identify your current compliance posture. Our AI advisory can answer specific questions about NIST SP 800-66 requirements, and cross-framework mapping helps you leverage existing controls from other frameworks you may already comply with. Create a free account to access all 8 controls and track your progress.

Start Your Compliance Journey

Create a free account to run self-assessments, get AI advisory, and track your compliance progress across 723 frameworks.

Get Started Free →

Free forever — no credit card required