Cross-Framework Mapping

FedRAMP Rev 5vs21 CFR Part 58 — Good Laboratory Practice (GLP)

See exactly how FedRAMP Rev 5 controls map to 21 CFR Part 58 — Good Laboratory Practice (GLP). Pre-computed mappings, identified gaps, and coverage analysis.

18
Controls Mapped
46
Gaps Found
17%
Coverage

According to the TheArtOfService Compliance Knowledge Graph:

FedRAMP Rev 5 maps to 21 CFR Part 58 — Good Laboratory Practice (GLP) with 17% coverage across 11 directly mapped controls. Analysis of 64 FedRAMP Rev 5 controls identifies 53 compliance gaps — primarily concentrated in Access Control and Authentication.

Source: TheArtOfService Knowledge Graph | 64 controls analysed | 693 frameworks | 819K+ cross-framework mappings

Control Mappings

Showing 18 of 18 mapped controls across 4 domains. Sign up to explore all 819K+ mappings across 693 frameworks.

System Protection and Communications(5 mappings)

3.10Physical and Environmental Protection
58.43Animal Care Facilities
FEDRAMP-CM-6Configuration Settings2 targets
58.1Scope
58.3Definitions
FEDRAMP-CP-9System Backup2 targets
58.1Scope
58.3Definitions

Access Control and Authentication(5 mappings)

FEDRAMP-AC-1Access Control Policy and Procedures2 targets
58.1Scope
58.3Definitions
FEDRAMP-AC-2Account Management2 targets
58.1Scope
58.3Definitions
ICS-AC-4Physical access controls
58.43Animal Care Facilities

Audit, Assessment and Risk(6 mappings)

FEDRAMP-AU-2Event Logging2 targets
58.1Scope
58.3Definitions
FEDRAMP-AU-6Audit Record Review, Analysis, and Reporting2 targets
58.1Scope
58.3Definitions
FEDRAMP-RA-5Vulnerability Monitoring and Scanning2 targets
58.1Scope
58.3Definitions

Personnel, Planning and Governance(2 mappings)

FEDRAMP-PE-3Physical Access Control
58.43Animal Care Facilities
FEDRAMP-PE-6Monitoring Physical Access
58.43Animal Care Facilities

Related Comparisons

Other FedRAMP Rev 5 comparisons

Other 21 CFR Part 58 — Good Laboratory Practice (GLP) comparisons

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What are the key differences between FedRAMP Rev 5 and 21 CFR Part 58 — Good Laboratory Practice (GLP)?

FedRAMP Rev 5 has 64 controls across its framework, while 21 CFR Part 58 — Good Laboratory Practice (GLP) covers 31 controls. Direct mapping analysis identifies 11 overlapping controls (17% coverage). The frameworks diverge most significantly in Access Control and Authentication, where 16 FedRAMP Rev 5 controls have no direct 21 CFR Part 58 — Good Laboratory Practice (GLP) equivalent.

How many controls map between FedRAMP Rev 5 and 21 CFR Part 58 — Good Laboratory Practice (GLP)?

Of 64 total FedRAMP Rev 5 controls, 11 map directly to 21 CFR Part 58 — Good Laboratory Practice (GLP) controls — representing 17% coverage. The remaining 53 controls represent compliance gaps requiring additional documentation or compensating controls to satisfy both frameworks simultaneously.

What are the compliance gaps when mapping FedRAMP Rev 5 to 21 CFR Part 58 — Good Laboratory Practice (GLP)?

53 FedRAMP Rev 5 controls have no direct equivalent in 21 CFR Part 58 — Good Laboratory Practice (GLP). The highest concentration of gaps is in Access Control and Authentication with 16 unmapped controls. These gaps represent areas where additional controls, policies, or documentation must be created to achieve compliance with both frameworks.

Which control domains have the most gaps between FedRAMP Rev 5 and 21 CFR Part 58 — Good Laboratory Practice (GLP)?

The domain with the highest gap count is Access Control and Authentication (16 gaps). Export the full domain-by-domain gap breakdown via the Professional tier to generate a prioritised remediation roadmap.

This platform provides educational compliance tools, not legal, regulatory, or professional compliance advice. Cross-framework mappings are AI-assisted interpretations and do not reproduce or replace official standards. Framework names and trademarks belong to their respective owners. Consult qualified professionals for your specific compliance requirements. See our Terms of Service.