Cross-Framework Mapping

US OFAC Sanctions Compliance Frameworkvs21 CFR Part 211 — Current Good Manufacturing Practice

See exactly how US OFAC Sanctions Compliance Framework controls map to 21 CFR Part 211 — Current Good Manufacturing Practice. Pre-computed mappings, identified gaps, and coverage analysis.

13
Controls Mapped
22
Gaps Found
14%
Coverage

According to the TheArtOfService Compliance Knowledge Graph:

US OFAC Sanctions Compliance Framework maps to 21 CFR Part 211 — Current Good Manufacturing Practice with 14% coverage across 5 directly mapped controls. Analysis of 35 US OFAC Sanctions Compliance Framework controls identifies 30 compliance gaps — primarily concentrated in Risk Assessment.

Source: TheArtOfService Knowledge Graph | 35 controls analysed | 693 frameworks | 819K+ cross-framework mappings

Control Mappings

Showing 13 of 13 mapped controls across 3 domains. Sign up to explore all 819K+ mappings across 693 frameworks.

Management Commitment(9 mappings)

2.1.1Management Policy3 targets
CFR211-C-48Section 211.48 — Plumbing
CFR211-F-113Section 211.113 — Control of Microbiological Contamination
CFR211-I-176Section 211.176 — Penicillin Contamination
2.1.2Management Responsibility3 targets
CFR211-C-48Section 211.48 — Plumbing
CFR211-F-113Section 211.113 — Control of Microbiological Contamination
CFR211-I-176Section 211.176 — Penicillin Contamination
2.1.3Food Safety and Quality Culture3 targets
CFR211-C-48Section 211.48 — Plumbing
CFR211-F-113Section 211.113 — Control of Microbiological Contamination
CFR211-I-176Section 211.176 — Penicillin Contamination

Risk Assessment(3 mappings)

DMF-4.2Risk Categorization3 targets
CFR211-G-122Section 211.122 — Materials Examination and Usage Criteria
CFR211-G-125Section 211.125 — Labeling Issuance
CFR211-G-130Section 211.130 — Packaging and Labeling Operations

Testing and Auditing(1 mappings)

TA-3Remediation of Findings
CFR211-A-3Section 211.3 — Definitions

Related Comparisons

Other US OFAC Sanctions Compliance Framework comparisons

Other 21 CFR Part 211 — Current Good Manufacturing Practice comparisons

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What are the key differences between US OFAC Sanctions Compliance Framework and 21 CFR Part 211 — Current Good Manufacturing Practice?

US OFAC Sanctions Compliance Framework has 35 controls across its framework, while 21 CFR Part 211 — Current Good Manufacturing Practice covers 57 controls. Direct mapping analysis identifies 5 overlapping controls (14% coverage). The frameworks diverge most significantly in Risk Assessment, where 12 US OFAC Sanctions Compliance Framework controls have no direct 21 CFR Part 211 — Current Good Manufacturing Practice equivalent.

How many controls map between US OFAC Sanctions Compliance Framework and 21 CFR Part 211 — Current Good Manufacturing Practice?

Of 35 total US OFAC Sanctions Compliance Framework controls, 5 map directly to 21 CFR Part 211 — Current Good Manufacturing Practice controls — representing 14% coverage. The remaining 30 controls represent compliance gaps requiring additional documentation or compensating controls to satisfy both frameworks simultaneously.

What are the compliance gaps when mapping US OFAC Sanctions Compliance Framework to 21 CFR Part 211 — Current Good Manufacturing Practice?

30 US OFAC Sanctions Compliance Framework controls have no direct equivalent in 21 CFR Part 211 — Current Good Manufacturing Practice. The highest concentration of gaps is in Risk Assessment with 12 unmapped controls. These gaps represent areas where additional controls, policies, or documentation must be created to achieve compliance with both frameworks.

Which control domains have the most gaps between US OFAC Sanctions Compliance Framework and 21 CFR Part 211 — Current Good Manufacturing Practice?

The domain with the highest gap count is Risk Assessment (12 gaps). Export the full domain-by-domain gap breakdown via the Professional tier to generate a prioritised remediation roadmap.

This platform provides educational compliance tools, not legal, regulatory, or professional compliance advice. Cross-framework mappings are AI-assisted interpretations and do not reproduce or replace official standards. Framework names and trademarks belong to their respective owners. Consult qualified professionals for your specific compliance requirements. See our Terms of Service.