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Cross-Framework Mapping

GAMP 5 — Good Automated Manufacturing PracticevsNIST SP 800-82 Rev 3 — Guide to OT Security

See exactly how GAMP 5 — Good Automated Manufacturing Practice controls map to NIST SP 800-82 Rev 3 — Guide to OT Security. Pre-computed mappings, identified gaps, and coverage analysis.

19
Controls Mapped
15
Gaps Found
32%
Coverage

According to the TheArtOfService Compliance Knowledge Graph:

GAMP 5 — Good Automated Manufacturing Practice maps to NIST SP 800-82 Rev 3 — Guide to OT Security with 32% coverage across 11 directly mapped controls. Analysis of 34 GAMP 5 — Good Automated Manufacturing Practice controls identifies 23 compliance gaps — primarily concentrated in Risk Management.

Source: TheArtOfService Knowledge Graph | 34 controls analysed | 693 frameworks | 819K+ cross-framework mappings

Control Mappings

Showing 19 of 19 mapped controls across 4 domains. Sign up to explore all 819K+ mappings across 693 frameworks.

Risk Management(12 mappings)

AESCSF-RM-2Risk Assessment Process2 targets
→NIST82-CTL-01OT Access Control
→NIST82-OVR-01OT System Characterization
CDP-RM-1Risk Identification Process2 targets
→NIST82-OVR-03OT Threat Assessment
→NIST82-OVR-04OT Vulnerability Assessment
CDP-RM-3Value Chain Risk Assessment2 targets
→NIST82-OVR-03OT Threat Assessment
→NIST82-OVR-04OT Vulnerability Assessment
FAA-CS-3.1Data-Driven Risk Management
→NIST82-RM-01OT-Specific Risk Management Framework
FAA-CS-3.2Supply Chain Risk Management2 targets
→NIST82-OVR-03OT Threat Assessment
→NIST82-RM-01OT-Specific Risk Management Framework
GAMP5-1.1Risk-Based Approach
→NIST82-RM-01OT-Specific Risk Management Framework
GAMP5-1.2Patient Safety Risk Assessment2 targets
→NIST82-OVR-03OT Threat Assessment
→NIST82-OVR-04OT Vulnerability Assessment

Lifecycle Approach (V-Model)(4 mappings)

GAMP5-3.1User Requirements Specification2 targets
→NIST82-IR-03OT Incident Containment
→NIST82-RM-02OT Security Program Management
GAMP5-3.3Design Specification2 targets
→NIST82-IR-03OT Incident Containment
→NIST82-RM-02OT Security Program Management

Operational Phase(2 mappings)

GAMP5-4.1Change and Configuration Management2 targets
→NIST82-CTL-05OT Configuration Management
→NIST82-RM-05OT Security Training and Awareness

Modern Technologies(1 mappings)

GAMP5-5.1Cloud Computing Validation
→NIST82-OVR-03OT Threat Assessment

Related Comparisons

Other GAMP 5 — Good Automated Manufacturing Practice comparisons

GAMP 5 — Good Automated Manufacturing Practice vs PAS 1192-5:2015 — Security-Minded Approach to BIM and Digital Built Environments10 mappingsGAMP 5 — Good Automated Manufacturing Practice vs Canada ITSG-33 — IT Security Risk Management10 mappingsGAMP 5 — Good Automated Manufacturing Practice vs New Zealand Information Security Manual (NZISM)10 mappingsGAMP 5 — Good Automated Manufacturing Practice vs MARS-E — Minimum Acceptable Risk Standards for Exchanges10 mappingsGAMP 5 — Good Automated Manufacturing Practice vs South Korea Cloud Security Assurance Program (CSAP)10 mappingsGAMP 5 — Good Automated Manufacturing Practice vs NRC 10 CFR 73.54 — Nuclear Facility Cybersecurity10 mappingsGAMP 5 — Good Automated Manufacturing Practice vs FedRAMP Rev 510 mappingsGAMP 5 — Good Automated Manufacturing Practice vs NIST SP 800-171A Rev 3 — Assessing CUI Security Requirements10 mappings

Other NIST SP 800-82 Rev 3 — Guide to OT Security comparisons

TISAX — Trusted Information Security Assessment Exchange vs NIST SP 800-82 Rev 3 — Guide to OT Security17 mappingsASD Information Security Manual (ISM) vs NIST SP 800-82 Rev 3 — Guide to OT Security17 mappingsCISA ICS-CERT Advisories and Industrial Control Systems Security Guidelines vs NIST SP 800-82 Rev 3 — Guide to OT Security17 mappingsNIST Cybersecurity Framework 2.0 vs NIST SP 800-82 Rev 3 — Guide to OT Security16 mappingsAPI 1164 vs NIST SP 800-82 Rev 3 — Guide to OT Security16 mappingsIEC 62443 vs NIST SP 800-82 Rev 3 — Guide to OT Security16 mappingsDO-326A / ED-202A vs NIST SP 800-82 Rev 3 — Guide to OT Security16 mappingsCSA CCM v4 vs NIST SP 800-82 Rev 3 — Guide to OT Security16 mappings

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What are the key differences between GAMP 5 — Good Automated Manufacturing Practice and NIST SP 800-82 Rev 3 — Guide to OT Security?

GAMP 5 — Good Automated Manufacturing Practice has 34 controls across its framework, while NIST SP 800-82 Rev 3 — Guide to OT Security covers 21 controls. Direct mapping analysis identifies 11 overlapping controls (32% coverage). The frameworks diverge most significantly in Risk Management, where 9 GAMP 5 — Good Automated Manufacturing Practice controls have no direct NIST SP 800-82 Rev 3 — Guide to OT Security equivalent.

How many controls map between GAMP 5 — Good Automated Manufacturing Practice and NIST SP 800-82 Rev 3 — Guide to OT Security?

Of 34 total GAMP 5 — Good Automated Manufacturing Practice controls, 11 map directly to NIST SP 800-82 Rev 3 — Guide to OT Security controls — representing 32% coverage. The remaining 23 controls represent compliance gaps requiring additional documentation or compensating controls to satisfy both frameworks simultaneously.

What are the compliance gaps when mapping GAMP 5 — Good Automated Manufacturing Practice to NIST SP 800-82 Rev 3 — Guide to OT Security?

23 GAMP 5 — Good Automated Manufacturing Practice controls have no direct equivalent in NIST SP 800-82 Rev 3 — Guide to OT Security. The highest concentration of gaps is in Risk Management with 9 unmapped controls. These gaps represent areas where additional controls, policies, or documentation must be created to achieve compliance with both frameworks.

Which control domains have the most gaps between GAMP 5 — Good Automated Manufacturing Practice and NIST SP 800-82 Rev 3 — Guide to OT Security?

The domain with the highest gap count is Risk Management (9 gaps). Export the full domain-by-domain gap breakdown via the Professional tier to generate a prioritised remediation roadmap.

Related Resources

How to Map Controls Across Frameworks|Multi-Framework Compliance Guide|Compliance Glossary

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