Cross-Framework Mapping

ICH E6(R3) — Good Clinical PracticevsNYDFS Cybersecurity Regulation (23 NYCRR Part 500)

See exactly how ICH E6(R3) — Good Clinical Practice controls map to NYDFS Cybersecurity Regulation (23 NYCRR Part 500). Pre-computed mappings, identified gaps, and coverage analysis.

16
Controls Mapped
1
Gaps Found
29%
Coverage

According to the TheArtOfService Compliance Knowledge Graph:

ICH E6(R3) — Good Clinical Practice maps to NYDFS Cybersecurity Regulation (23 NYCRR Part 500) with 29% coverage across 5 directly mapped controls. Analysis of 17 ICH E6(R3) — Good Clinical Practice controls identifies 12 compliance gaps — primarily concentrated in Overarching Principles.

Source: TheArtOfService Knowledge Graph | 17 controls analysed | 693 frameworks | 819K+ cross-framework mappings

Control Mappings

Showing 16 of 16 mapped controls across 4 domains. Sign up to explore all 819K+ mappings across 693 frameworks.

Annex 1 - Data Governance(11 mappings)

E6R3-A1.10Electronic Systems and Records6 targets
314.4(c)(8)Monitoring and logging
HIPAA-164.312(c)(1)Integrity
HIPAA-164.312(d)Person or entity authentication
HIPAA-164.312(e)(1)Transmission security
NYDFS-500-CLA-3Endpoint Detection and Response
NYDFS-500.14Monitoring and Logging
E6R3-A1.9Data Governance Framework5 targets
HIPAA-164.312(c)(1)Integrity
HIPAA-164.312(d)Person or entity authentication
HIPAA-164.312(e)(1)Transmission security
NYDFS-500.13Asset Management and Data Governance
NYDFS-500.3Cybersecurity Policy

Annex 1 - Sponsor Responsibilities(1 mappings)

E6R3-A1.8Safety Reporting
NYDFS-500.2bProgram Core Functions

Annex 2 - Non-Traditional Interventional Clinical Trials(3 mappings)

E6R3-A2.1Decentralized Trials3 targets
HIPAA-164.312(c)(1)Integrity
HIPAA-164.312(d)Person or entity authentication
HIPAA-164.312(e)(1)Transmission security

Overarching Principles(1 mappings)

E6R3-P2Risk Proportionality
NYDFS-500.4cSenior Governing Body Oversight

Related Comparisons

Other ICH E6(R3) — Good Clinical Practice comparisons

Other NYDFS Cybersecurity Regulation (23 NYCRR Part 500) comparisons

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What are the key differences between ICH E6(R3) — Good Clinical Practice and NYDFS Cybersecurity Regulation (23 NYCRR Part 500)?

ICH E6(R3) — Good Clinical Practice has 17 controls across its framework, while NYDFS Cybersecurity Regulation (23 NYCRR Part 500) covers 35 controls. Direct mapping analysis identifies 5 overlapping controls (29% coverage). The frameworks diverge most significantly in Overarching Principles, where 4 ICH E6(R3) — Good Clinical Practice controls have no direct NYDFS Cybersecurity Regulation (23 NYCRR Part 500) equivalent.

How many controls map between ICH E6(R3) — Good Clinical Practice and NYDFS Cybersecurity Regulation (23 NYCRR Part 500)?

Of 17 total ICH E6(R3) — Good Clinical Practice controls, 5 map directly to NYDFS Cybersecurity Regulation (23 NYCRR Part 500) controls — representing 29% coverage. The remaining 12 controls represent compliance gaps requiring additional documentation or compensating controls to satisfy both frameworks simultaneously.

What are the compliance gaps when mapping ICH E6(R3) — Good Clinical Practice to NYDFS Cybersecurity Regulation (23 NYCRR Part 500)?

12 ICH E6(R3) — Good Clinical Practice controls have no direct equivalent in NYDFS Cybersecurity Regulation (23 NYCRR Part 500). The highest concentration of gaps is in Overarching Principles with 4 unmapped controls. These gaps represent areas where additional controls, policies, or documentation must be created to achieve compliance with both frameworks.

Which control domains have the most gaps between ICH E6(R3) — Good Clinical Practice and NYDFS Cybersecurity Regulation (23 NYCRR Part 500)?

The domain with the highest gap count is Overarching Principles (4 gaps). Export the full domain-by-domain gap breakdown via the Professional tier to generate a prioritised remediation roadmap.

This platform provides educational compliance tools, not legal, regulatory, or professional compliance advice. Cross-framework mappings are AI-assisted interpretations and do not reproduce or replace official standards. Framework names and trademarks belong to their respective owners. Consult qualified professionals for your specific compliance requirements. See our Terms of Service.