TheArtOfService
Cross-Framework Mapping

21 CFR Part 211 — Current Good Manufacturing PracticevsProtective Security Policy Framework (PSPF) Release 2024

See exactly how 21 CFR Part 211 — Current Good Manufacturing Practice controls map to Protective Security Policy Framework (PSPF) Release 2024. Pre-computed mappings, identified gaps, and coverage analysis.

12
Controls Mapped
45
Gaps Found
9%
Coverage

According to the TheArtOfService Compliance Knowledge Graph:

21 CFR Part 211 — Current Good Manufacturing Practice maps to Protective Security Policy Framework (PSPF) Release 2024 with 9% coverage across 5 directly mapped controls. Analysis of 57 21 CFR Part 211 — Current Good Manufacturing Practice controls identifies 52 compliance gaps — primarily concentrated in Subpart F — Production and Process Controls.

Source: TheArtOfService Knowledge Graph | 57 controls analysed | 693 frameworks | 819K+ cross-framework mappings

Control Mappings

Showing 12 of 12 mapped controls across 3 domains. Sign up to explore all 819K+ mappings across 693 frameworks.

Subpart A — General Provisions(3 mappings)

CFR211-A-3Section 211.3 — Definitions3 targets
→DSPF-GOV-6Security Accountability
→EIOPA-GL-10ICT Operations Security
→PSPF-GOV-2Management Structures and Responsibilities

Subpart G — Packaging and Labeling Control(3 mappings)

CFR211-G-122Section 211.122 — Materials Examination and Usage Criteria
→DSPF-INFO-1Information Classification
CFR211-G-125Section 211.125 — Labeling Issuance
→DSPF-INFO-1Information Classification
CFR211-G-130Section 211.130 — Packaging and Labeling Operations
→DSPF-INFO-1Information Classification

Subpart J — Records and Reports(6 mappings)

CFR211-J-184Section 211.184 — Component, Drug Product Container, Closure, and Labeling Records6 targets
→AEO-PS-2Security Awareness Training
→CTPAT-PE-1Pre-Employment Verification
→CTPAT-PE-3Education and Training
→PSPF-DIR-001-2024Direction 001-2024: Foreign Ownership, Control or Influence — Technology Assets
→SEMD-PS-3Supply Chain Security
→TISAX-IS-03Third-Party Risk Management

Related Comparisons

Other 21 CFR Part 211 — Current Good Manufacturing Practice comparisons

21 CFR Part 211 — Current Good Manufacturing Practice vs FDA Quality Management System Regulation (QMSR)8 mappings21 CFR Part 211 — Current Good Manufacturing Practice vs US OFAC Sanctions Compliance Framework7 mappings21 CFR Part 211 — Current Good Manufacturing Practice vs CFTC System Safeguards (17 CFR 37, 38, 39, 49)5 mappings21 CFR Part 211 — Current Good Manufacturing Practice vs GLI-33 — Gaming Laboratories International Event Wagering Systems5 mappings21 CFR Part 211 — Current Good Manufacturing Practice vs EIOPA Guidelines on ICT Security and Governance (2023)5 mappings21 CFR Part 211 — Current Good Manufacturing Practice vs TISAX — Trusted Information Security Assessment Exchange5 mappings21 CFR Part 211 — Current Good Manufacturing Practice vs Telecommunications Sector Security Reforms (TSSR)5 mappings21 CFR Part 211 — Current Good Manufacturing Practice vs Defence Security Principles Framework (DSPF)5 mappings

Other Protective Security Policy Framework (PSPF) Release 2024 comparisons

Defence Security Principles Framework (DSPF) vs Protective Security Policy Framework (PSPF) Release 202439 mappingsTISAX — Trusted Information Security Assessment Exchange vs Protective Security Policy Framework (PSPF) Release 202439 mappingsNIS2 Directive Implementing Acts vs Protective Security Policy Framework (PSPF) Release 202437 mappingsSouth Korea Cloud Security Assurance Program (CSAP) vs Protective Security Policy Framework (PSPF) Release 202436 mappingsNIST SP 800-82 Rev 3 — Guide to OT Security vs Protective Security Policy Framework (PSPF) Release 202436 mappingsNIST SP 800-171A Rev 3 — Assessing CUI Security Requirements vs Protective Security Policy Framework (PSPF) Release 202436 mappingsCFTC System Safeguards (17 CFR 37, 38, 39, 49) vs Protective Security Policy Framework (PSPF) Release 202436 mappingsPAS 1192-5:2015 — Security-Minded Approach to BIM and Digital Built Environments vs Protective Security Policy Framework (PSPF) Release 202435 mappings

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What are the key differences between 21 CFR Part 211 — Current Good Manufacturing Practice and Protective Security Policy Framework (PSPF) Release 2024?

21 CFR Part 211 — Current Good Manufacturing Practice has 57 controls across its framework, while Protective Security Policy Framework (PSPF) Release 2024 covers 91 controls. Direct mapping analysis identifies 5 overlapping controls (9% coverage). The frameworks diverge most significantly in Subpart F — Production and Process Controls, where 8 21 CFR Part 211 — Current Good Manufacturing Practice controls have no direct Protective Security Policy Framework (PSPF) Release 2024 equivalent.

How many controls map between 21 CFR Part 211 — Current Good Manufacturing Practice and Protective Security Policy Framework (PSPF) Release 2024?

Of 57 total 21 CFR Part 211 — Current Good Manufacturing Practice controls, 5 map directly to Protective Security Policy Framework (PSPF) Release 2024 controls — representing 9% coverage. The remaining 52 controls represent compliance gaps requiring additional documentation or compensating controls to satisfy both frameworks simultaneously.

What are the compliance gaps when mapping 21 CFR Part 211 — Current Good Manufacturing Practice to Protective Security Policy Framework (PSPF) Release 2024?

52 21 CFR Part 211 — Current Good Manufacturing Practice controls have no direct equivalent in Protective Security Policy Framework (PSPF) Release 2024. The highest concentration of gaps is in Subpart F — Production and Process Controls with 8 unmapped controls. These gaps represent areas where additional controls, policies, or documentation must be created to achieve compliance with both frameworks.

Which control domains have the most gaps between 21 CFR Part 211 — Current Good Manufacturing Practice and Protective Security Policy Framework (PSPF) Release 2024?

The domain with the highest gap count is Subpart F — Production and Process Controls (8 gaps). Export the full domain-by-domain gap breakdown via the Professional tier to generate a prioritised remediation roadmap.

Related Resources

How to Map Controls Across Frameworks|Multi-Framework Compliance Guide|Compliance Glossary

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