Cross-Framework Mapping

EU Medical Devices Regulation (MDR 2017/745)vsICH E6(R3) — Good Clinical Practice

See exactly how EU Medical Devices Regulation (MDR 2017/745) controls map to ICH E6(R3) — Good Clinical Practice. Pre-computed mappings, identified gaps, and coverage analysis.

15
Controls Mapped
5
Gaps Found
40%
Coverage

According to the TheArtOfService Compliance Knowledge Graph:

EU Medical Devices Regulation (MDR 2017/745) maps to ICH E6(R3) — Good Clinical Practice with 40% coverage across 8 directly mapped controls. Analysis of 20 EU Medical Devices Regulation (MDR 2017/745) controls identifies 12 compliance gaps — primarily concentrated in Chapter VII — Post-Market Surveillance.

Source: TheArtOfService Knowledge Graph | 20 controls analysed | 693 frameworks | 819K+ cross-framework mappings

Control Mappings

Showing 15 of 15 mapped controls across 4 domains. Sign up to explore all 819K+ mappings across 693 frameworks.

Annex I — General Safety and Performance Requirements(5 mappings)

MDR-AI-01Risk Management
E6R3-P2Risk Proportionality
MDR-AI-03Infection and Microbial Contamination
E6R3-A1.9Data Governance Framework
MDR-AI-05Clinical Evaluation3 targets
E6R3-A1.10Electronic Systems and Records
E6R3-A1.9Data Governance Framework
E6R3-A2.1Decentralized Trials

Chapter II — Device Classification and Conformity(3 mappings)

MDR-II-01Device Classification Rules3 targets
E6R3-A1.10Electronic Systems and Records
E6R3-A1.9Data Governance Framework
E6R3-A2.1Decentralized Trials

Chapter III — Economic Operators(6 mappings)

MDR-III-01Manufacturer General Obligations
E6R3-A1.6Quality Management System
MDR-III-02Person Responsible for Regulatory Compliance4 targets
E6R3-A1.10Electronic Systems and Records
E6R3-A1.6Quality Management System
E6R3-A1.9Data Governance Framework
E6R3-A2.1Decentralized Trials
MDR-III-04Traceability Requirements
E6R3-A1.9Data Governance Framework

Chapter VII — Post-Market Surveillance(1 mappings)

MDR-VII-02Periodic Safety Update Report (PSUR)
E6R3-A1.6Quality Management System

Related Comparisons

Other EU Medical Devices Regulation (MDR 2017/745) comparisons

Other ICH E6(R3) — Good Clinical Practice comparisons

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What are the key differences between EU Medical Devices Regulation (MDR 2017/745) and ICH E6(R3) — Good Clinical Practice?

EU Medical Devices Regulation (MDR 2017/745) has 20 controls across its framework, while ICH E6(R3) — Good Clinical Practice covers 17 controls. Direct mapping analysis identifies 8 overlapping controls (40% coverage). The frameworks diverge most significantly in Chapter VII — Post-Market Surveillance, where 4 EU Medical Devices Regulation (MDR 2017/745) controls have no direct ICH E6(R3) — Good Clinical Practice equivalent.

How many controls map between EU Medical Devices Regulation (MDR 2017/745) and ICH E6(R3) — Good Clinical Practice?

Of 20 total EU Medical Devices Regulation (MDR 2017/745) controls, 8 map directly to ICH E6(R3) — Good Clinical Practice controls — representing 40% coverage. The remaining 12 controls represent compliance gaps requiring additional documentation or compensating controls to satisfy both frameworks simultaneously.

What are the compliance gaps when mapping EU Medical Devices Regulation (MDR 2017/745) to ICH E6(R3) — Good Clinical Practice?

12 EU Medical Devices Regulation (MDR 2017/745) controls have no direct equivalent in ICH E6(R3) — Good Clinical Practice. The highest concentration of gaps is in Chapter VII — Post-Market Surveillance with 4 unmapped controls. These gaps represent areas where additional controls, policies, or documentation must be created to achieve compliance with both frameworks.

Which control domains have the most gaps between EU Medical Devices Regulation (MDR 2017/745) and ICH E6(R3) — Good Clinical Practice?

The domain with the highest gap count is Chapter VII — Post-Market Surveillance (4 gaps). Export the full domain-by-domain gap breakdown via the Professional tier to generate a prioritised remediation roadmap.

This platform provides educational compliance tools, not legal, regulatory, or professional compliance advice. Cross-framework mappings are AI-assisted interpretations and do not reproduce or replace official standards. Framework names and trademarks belong to their respective owners. Consult qualified professionals for your specific compliance requirements. See our Terms of Service.