Australia National Pathology Standards (First Edition 2027) 10.03: Measurement uncertainty process: for quantitative assays define the measurand, indicate the laboratory's confidence in each measurement, provide information for interpreting results and comparing them over time, set clinically appropriate imprecision goals, identify significant uncertainty sources and reduction opportunities, and use statistically adequate replicate numbers or statistical methods that account for fewer replicates

What does 10.03 require?

Measurement uncertainty is estimated for quantitative assays by a process that states what quantity is being measured, expresses how confident the laboratory is in each measurement, gives what is needed to interpret results and compare them over time, sets imprecision goals that make clinical sense, finds the main contributors to uncertainty and ways to shrink them, and rests on enough replicate measurements for statistical validity or on statistics that allow for fewer replicates.