OSHA General Industry Standards (29 CFR Part 1910)
Subpart Z: Toxic and Hazardous Substances – OSHA General Industry Standards (29 CFR Part 1910)

OSHA General Industry Standards (29 CFR Part 1910) 1910.1450: 1910.1450 Occupational exposure to hazardous chemicals in laboratories

Applies to employers engaged in laboratory use of hazardous chemicals, meaning laboratory-scale manipulations (containers one person can easily and safely handle), multiple chemicals or procedures, not part of or simulating a production process, with protective laboratory practices and equipment in common use. Hazardous chemical means one classified under 1910.1200 as a health hazard or simple asphyxiant. For laboratories it supersedes the other Subpart Z health standards except that their PELs still apply, their prohibitions of eye and skin contact must be observed, and where a substance's action level (or PEL) is routinely exceeded the monitoring and medical surveillance provisions of that standard apply. It does not apply to uses that are not laboratory use (the relevant Subpart Z standard applies even inside a laboratory) or to uses with no exposure potential such as dip-and-read test strips and sealed commercial test kits. Exposures must not exceed Subpart Z PELs. The employer must measure exposure to a substance whose standard requires monitoring if there is reason to believe levels routinely exceed the action level (or PEL); if initial monitoring shows exposure over it, the employer must immediately follow that standard's monitoring provisions, and may terminate as that standard allows. Results go to employees in writing, individually or by posting, within 15 working days. Where hazardous chemicals are used, the employer must develop and carry out a written Chemical Hygiene Plan capable of protecting employees from the health hazards and keeping exposures below the PELs, readily available to employees and their representatives and to OSHA on request, and reviewed and evaluated at least annually. It must include standard operating procedures; criteria for choosing engineering controls, PPE and hygiene practices with attention to extremely hazardous chemicals; a requirement and specific measures to ensure fume hoods and other protective equipment function properly; information and training provisions; circumstances requiring prior approval before a procedure starts; medical consultation and examination provisions; designation of responsible personnel including a Chemical Hygiene Officer and, where appropriate, a committee; and additional protection for particularly hazardous substances (select carcinogens, reproductive toxins, highly acutely toxic substances), including where appropriate a designated area, containment devices such as hoods or glove boxes, safe waste removal and decontamination procedures. Information and training are given at initial assignment to a work area with hazardous chemicals and before new exposure situations, with refresher frequency set by the employer; employees learn the standard and its appendices, where the plan is, PELs or recommended limits, signs and symptoms, and reference material including SDSs, and are trained in detection methods, physical and health hazards, protective measures and the details of the plan. Medical attention, by or under the direct supervision of a licensed physician at no cost, without loss of pay and at a reasonable time and place, must be offered when an employee develops signs or symptoms of exposure, when monitoring shows routine exposure above an action level (or PEL) for a substance with surveillance requirements (surveillance then follows that standard), and as a consultation after a spill, leak, explosion or other event likely to cause hazardous exposure. The physician receives the chemical identity, exposure conditions and symptoms, and gives a written opinion (follow-up recommendations, results, conditions of increased risk, statement that the employee was informed) without unrelated findings. Labels on incoming containers must not be removed or defaced and SDSs received with shipments kept readily accessible; a chemical of known composition made for the laboratory's own use must be assessed and, if hazardous, covered by training, unknown byproducts assumed hazardous, and chemicals made for outside users handled under the HCS. Respirators needed to stay below PELs are provided at no cost under 1910.134. Records of exposure measurements and medical consultations and examinations are kept, transferred and made available under 1910.20 (1910.1020). Appendix A (National Research Council Prudent Practices recommendations) and Appendix B (references) are non-mandatory.

Maintained by Gerard Blokdyk

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  • 262.214 § 262.214 Laboratory management plan

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Other controls in Subpart Z: Toxic and Hazardous Substances – OSHA General Industry Standards (29 CFR Part 1910)

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