OSHA General Industry Standards (29 CFR Part 1910) 1910.1003: 1910.1003 13 Carcinogens (4-Nitrobiphenyl, etc.)

Covers any area where the 13 carcinogens are manufactured, processed, repackaged, released, handled or stored: 4-nitrobiphenyl, alpha-naphthylamine (1910.1004), methyl chloromethyl ether (1910.1006), 3,3'-dichlorobenzidine and its salts (1910.1007), bis-chloromethyl ether (1910.1008), beta-naphthylamine (1910.1009), benzidine (1910.1010), 4-aminodiphenyl (1910.1011), ethyleneimine (1910.1012), beta-propiolactone (1910.1013), 2-acetylaminofluorene (1910.1014), 4-dimethylaminoazobenzene (1910.1015) and N-nitrosodimethylamine (1910.1016); those pointer sections simply refer back here. Transshipment in sealed containers is excluded except for labeling. Mixtures below 0.1 percent (4-nitrobiphenyl, methyl chloromethyl ether, bis-chloromethyl ether, beta-naphthylamine, benzidine, 4-aminodiphenyl) or below 1.0 percent (the other seven) by weight or volume are exempt. The standard sets no numerical exposure limit; control is by regulated areas and containment. A regulated area with restricted, controlled entry must be set up wherever a covered carcinogen is present, controlled by operation type: isolated systems (glove box) require hand and arm washing after the task; closed systems restrict access to authorized employees and, for nine of the substances, require washing of hands, forearms, face and neck on each exit. Open-vessel system operations are prohibited. For transfer, charging, discharging or laboratory-type hood operations: authorized access only; continuous local exhaust so air always moves from work areas toward the operation, with exhaust decontaminated before discharge and clean makeup air; clean full-body protective clothing, shoe covers and gloves before entry; a NIOSH-certified half-mask air-purifying respirator with particulate filters for 4-nitrobiphenyl, alpha-naphthylamine, 3,3'-dichlorobenzidine, beta-naphthylamine, benzidine, 4-aminodiphenyl, 2-acetylaminofluorene, 4-dimethylaminoazobenzene and N-nitrosodimethylamine, and a pressure-demand full-facepiece SCBA or supplied-air respirator with auxiliary SCBA for methyl chloromethyl ether, bis-chloromethyl ether, ethyleneimine and beta-propiolactone; clothing left in impervious labelled containers at exit; no drinking fountains; washing on each exit, and a shower after the last exit of the day for those nine substances. Maintenance, spill clean-up and decontamination work requires impervious garments, gloves, boots and a continuous-air supplied hood, decontamination before removal and a shower. General requirements: respiratory protection program under 1910.134; emergency evacuation, decontamination before resuming, special medical surveillance by a physician within 24 hours for those present, showering after known contact, and deluge showers and eyewash near ethyleneimine and beta-propiolactone points; no food, beverages, cosmetics or tobacco in regulated areas; washing, shower and change facilities per 1910.141; toilets in regulated areas in a separate room; regulated areas (except outdoor systems) under negative pressure with equal clean makeup air; decontamination procedures; no dry sweeping or mopping for the nine listed substances. Hazard communication under 1910.1200 with listed hazards for each substance; DANGER (CHEMICAL IDENTIFICATION) MAY CAUSE CANCER signs at regulated area entrances plus entry and exit instructions; no contradicting statements. Training and indoctrination before authorization to enter, reviewing this section at the first program and annually thereafter; emergency procedures posted and rehearsed. Medical surveillance at no cost: preassignment physical with personal, family and occupational history, periodic examinations not less often than annually, physician to consider increased-risk conditions (reduced immunological competence, steroid or cytotoxic treatment, pregnancy, smoking) and furnish a suitability statement; medical records kept for the duration of employment.