Article 15 establishes that substantial modifications require prior authorisation. Article 16 sets the application requirements (submission via CTIS). Article 17 sets the 6-day validation period for substantial-modification applications. Articles 18-24 cover the Part I / Part II / combined assessment, decision, and persons-assessing-the-application provisions for substantial modifications.
The graph holds this control, the 0 it maps to, and the evidence behind each claim, over MCP and REST.